Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
DGUA_6G018081Blast:Type I inositol 1,4,5-trisphosphate 5-phosphatase. (689 aa)    
Predicted Functional Partners:
DGUA_6G020082
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.988
DGUA_6G004157
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.988
DGUA_6G019685
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
 0.986
DGUA_6G018943
Blast:Type I inositol 3,4-bisphosphate 4-phosphatase.
     
 0.986
DGUA_6G020648
Blast:Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A.
     
 0.984
DGUA_6G012631
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.983
DGUA_6G012578
Phosphoinositide phospholipase C.
   
 
 0.982
DGUA_6G010302
Blast:Multiple inositol polyphosphate phosphatase 1.
     
  0.976
DGUA_6G009438
Blast:Multiple inositol polyphosphate phosphatase 1; Belongs to the histidine acid phosphatase family.
     
  0.976
DGUA_6G015930
Blast:Inositol polyphosphate 1-phosphatase.
     
 0.976
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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