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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
DGUA_6G016322Ubiquitin carboxyl-terminal hydrolase. (903 aa)    
Predicted Functional Partners:
DGUA_6G015274
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.984
DGUA_6G013463
Blast:Signal transducing adapter molecule 1.
    
 0.982
DGUA_6G003161
Receptor protein-tyrosine kinase.
    
 0.977
DGUA_6G013769
Blast:Protein smoothened; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.970
DGUA_6G014889
Blast:E3 ubiquitin-protein ligase NRDP1.
    
 0.967
DGUA_6G014160
Blast:E3 ubiquitin-protein ligase NRDP1.
    
 0.967
DGUA_6G013613
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
   
 0.920
DGUA_6G015444
Blast:Baculoviral IAP repeat-containing protein 6.
   
 0.886
DGUA_6G015151
Blast:Polyubiquitin.
   
 0.876
DGUA_6G008901
Blast:Polyubiquitin.
   
 0.876
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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