Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G014889Blast:E3 ubiquitin-protein ligase NRDP1. (324 aa)    
Predicted Functional Partners:
DGUA_6G003161
Receptor protein-tyrosine kinase.
    
 0.991
DGUA_6G015190
Blast:E3 ubiquitin-protein ligase CBL-B.
    
 0.981
DGUA_6G002774
Blast:E3 ubiquitin-protein ligase Smurf1.
    
 0.980
DGUA_6G012142
Blast:E3 ubiquitin-protein ligase Su(Dx).
    
 0.978
DGUA_6G009705
Blast:E3 ubiquitin-protein ligase Nedd-4.
    
 0.978
DGUA_6G016390
Blast:Insulin-like receptor.
    
 0.978
DGUA_6G018676
Blast:TNF receptor-associated factor 6.
    
 0.978
DGUA_6G014160
Blast:E3 ubiquitin-protein ligase NRDP1.
     
  0.977
DGUA_6G016322
Ubiquitin carboxyl-terminal hydrolase.
    
 0.967
DGUA_6G015444
Blast:Baculoviral IAP repeat-containing protein 6.
    
 0.937
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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