STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G014450Uncharacterized protein. (366 aa)    
Predicted Functional Partners:
DGUA_6G015277
Blast:Asparagine synthetase.
     
 0.729
DGUA_6G012156
Aspartate aminotransferase.
   
 
 0.626
DGUA_6G001102
Blast:Sphingosine-1-phosphate lyase.
     
 0.625
DGUA_6G016006
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
    
  0.625
DGUA_6G005958
Blast:Transcription initiation factor IIA subunit 1.
      
 0.531
DGUA_6G014550
Blast:Retinoblastoma-binding protein 5 homolog.
      
 0.508
DGUA_6G015890
Histone-lysine N-methyltransferase trithorax; Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes. Acts as an activator of BX-C. Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo.
    
 
 0.464
DGUA_6G007268
Blast:Protein FAM49B.
      
 0.443
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.