STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G015378Blast:Aromatic-amino-acid aminotransferase 1. (420 aa)    
Predicted Functional Partners:
DGUA_6G012156
Aspartate aminotransferase.
  
 0.956
cn
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
   
 
 0.956
DGUA_6G003611
Blast:Peroxisomal (S)-2-hydroxy-acid oxidase GLO5.
  
 
 0.956
DGUA_6G019992
Blast:Kynurenine--oxoglutarate transaminase 3.
  
 0.953
DGUA_6G001373
Blast:YrdC domain-containing protein, mitochondrial.
  
 
 0.943
DGUA_6G007786
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.936
DGUA_6G020936
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.
   
 
 0.930
DGUA_6G011367
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.913
DGUA_6G007118
Blast:Alpha-aminoadipic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.910
DGUA_6G017546
Uncharacterized protein.
     
 0.904
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.