Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hagAMembrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (344 aa)    
Predicted Functional Partners:
skp
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.940
secA
Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
 
 0.873
tolB
Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.827
degQ
Serine peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
   
 
 0.787
degS
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.787
yaeT
Outer membrane protein assembly protein YaeT; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
 
 0.776
ompD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.681
matP
Ter macrodomain organizer matS-binding protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.667
BamE
Plastocyanin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
0.645
KKA99575.1
Porin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.640
Your Current Organism:
Avibacterium paragallinarum
NCBI taxonomy Id: 728
Other names: A. paragallinarum, ATCC 29545, CCUG 12835, CIP 103453, DSM 18554, Haemophilus gallinarum, Haemophilus paragallinarum, NCTC 11296
Server load: low (12%) [HD]