STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKA98648.1Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)    
Predicted Functional Partners:
kbaZ
Tagatose-bisphosphate aldolase; With KbaY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1,6-bisphosphate; subunit Z may act as a chaperone for the Y subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.919
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.904
eda
2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
agaS
Sugar isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.729
nagA_1
N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.714
KKA98642.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.672
KKA98646.1
Transcriptional repressor for the agaZVWA and agaSYBCDI operons; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.660
KKA99586.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.635
KKA98645.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.564
KKA99178.1
Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.459
Your Current Organism:
Avibacterium paragallinarum
NCBI taxonomy Id: 728
Other names: A. paragallinarum, ATCC 29545, CCUG 12835, CIP 103453, DSM 18554, Haemophilus gallinarum, Haemophilus paragallinarum, NCTC 11296
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