Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
selASelenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (464 aa)    
Predicted Functional Partners:
selD
Catalyzes the formation of selenophosphate from selenide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.985
selB_3
Translation elongation factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.977
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
     
 0.943
AKU63939.1
Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.741
AKU63940.1
Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.740
fdhE
Formate dehydrogenase; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
   
 0.691
AKU62701.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.632
fdoH_1
Formate dehydrogenase; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
 
  
 0.566
fdnI
Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.562
AKU63311.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.526
Your Current Organism:
Aggregatibacter aphrophilus
NCBI taxonomy Id: 732
Other names: A. aphrophilus, ATCC 29241 [[Haemophilus paraphrophilus]], ATCC 33389, CCUG 3715, CCUG 41355 [[Haemophilus paraphrophilus]], CIP 70.72 [[Haemophilus paraphrophilus]], CIP 70.73, Haemophilus aphrophilus, Haemophilus paraphrophilus, NCTC 10557 [[Haemophilus paraphrophilus]], NCTC 5906
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