STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GX50_07337tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (310 aa)    
Predicted Functional Partners:
GX50_00921
tRNA-splicing endonuclease subunit Sen54.
   
 0.896
CLP1
mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.
    
 0.796
GX50_04001
Sen15 domain-containing protein.
    
 0.775
GX50_03981
RNase_PH domain-containing protein.
 
      0.743
GX50_00537
tRNA-intron endonuclease.
     
 0.662
GX50_02928
Sulfite reductase (NADPH) hemoprotein beta-component.
   
    0.627
GX50_02582
3-hydroxyisobutyrate dehydrogenase.
 
      0.598
GX50_00570
Cleavage stimulation factor subunit 2.
    
  0.587
GX50_00940
Uncharacterized protein.
    
  0.557
GX50_06164
Ribonuclease Z.
  
  
 0.553
Your Current Organism:
Emmonsia crescens
NCBI taxonomy Id: 73230
Other names: ATCC 13704, Ajellomyces crescens, CBS 177.60, Chrysosporium parvum var. crescens, E. crescens, Emmonsia parva var. crescens, UAMH 3008
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