STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GX50_00681tRNA (Guanine37-N1)-methyltransferase. (915 aa)    
Predicted Functional Partners:
TRM5
tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.
 
      0.897
GX50_00551
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
 
      0.860
GX50_00695
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
 
      0.804
GX50_08840
Vesicle-associated membrane protein 4.
    
 0.709
GX50_04743
Cation-dependent mannose-6-phosphate receptor.
    
 0.670
GX50_03444
Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.
    
 0.656
GX50_06663
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.649
GX50_04113
Vacuolar protein sorting-associated protein 29; Belongs to the VPS29 family.
    
 
 0.648
GX50_04311
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.646
GX50_05041
Uncharacterized protein.
    
 
 0.644
Your Current Organism:
Emmonsia crescens
NCBI taxonomy Id: 73230
Other names: ATCC 13704, Ajellomyces crescens, CBS 177.60, Chrysosporium parvum var. crescens, E. crescens, Emmonsia parva var. crescens, UAMH 3008
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.