GX50_01031 protein (Emmonsia crescens) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Score

GX50_01031

Tubulin-specific chaperone A; Belongs to the TBCA family. (120 aa)

Predicted Functional Partners:

GX50_05495

0.860

GX50_02425

0.860

GX50_06989

0.815

GX50_04524

0.606

GX50_06342

0.589

GX50_04231

0.583

GX50_00198

0.583

GX50_03209

0.580

GX50_03376

0.580

GX50_01282

0.579

Your Current Organism:

Emmonsia crescens

NCBI taxonomy Id: 73230
Other names: ATCC 13704, Ajellomyces crescens, CBS 177.60, Chrysosporium parvum var. crescens, E. crescens, Emmonsia parva var. crescens, UAMH 3008

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GX50_00198	GX50_01031	A0A2B7ZUV4	A0A2B7ZR88	TFCD_C domain-containing protein.	Tubulin-specific chaperone A; Belongs to the TBCA family.	0.583
GX50_00198	GX50_02425	A0A2B7ZUV4	A0A2B7ZM68	TFCD_C domain-containing protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.567
GX50_00198	GX50_03209	A0A2B7ZUV4	A0A2B7ZLU6	TFCD_C domain-containing protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.537
GX50_00198	GX50_03376	A0A2B7ZUV4	A0A2B7ZLX2	TFCD_C domain-containing protein.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.537
GX50_00198	GX50_05495	A0A2B7ZUV4	A0A2B7ZCM4	TFCD_C domain-containing protein.	Centromere protein I.	0.498
GX50_00198	GX50_06342	A0A2B7ZUV4	A0A2B7ZDI2	TFCD_C domain-containing protein.	Uncharacterized protein.	0.599
GX50_00198	GX50_06989	A0A2B7ZUV4	A0A2B7ZA19	TFCD_C domain-containing protein.	CAP-Gly domain-containing protein.	0.928
GX50_01031	GX50_00198	A0A2B7ZR88	A0A2B7ZUV4	Tubulin-specific chaperone A; Belongs to the TBCA family.	TFCD_C domain-containing protein.	0.583
GX50_01031	GX50_01282	A0A2B7ZR88	A0A2B7ZH68	Tubulin-specific chaperone A; Belongs to the TBCA family.	Prefoldin subunit 2.	0.579
GX50_01031	GX50_02425	A0A2B7ZR88	A0A2B7ZM68	Tubulin-specific chaperone A; Belongs to the TBCA family.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.860
GX50_01031	GX50_03209	A0A2B7ZR88	A0A2B7ZLU6	Tubulin-specific chaperone A; Belongs to the TBCA family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.580
GX50_01031	GX50_03376	A0A2B7ZR88	A0A2B7ZLX2	Tubulin-specific chaperone A; Belongs to the TBCA family.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.580
GX50_01031	GX50_04231	A0A2B7ZR88	A0A2B7ZID7	Tubulin-specific chaperone A; Belongs to the TBCA family.	Uncharacterized protein.	0.583
GX50_01031	GX50_04524	A0A2B7ZR88	A0A2B7ZIP0	Tubulin-specific chaperone A; Belongs to the TBCA family.	Prefoldin subunit 1.	0.606
GX50_01031	GX50_05495	A0A2B7ZR88	A0A2B7ZCM4	Tubulin-specific chaperone A; Belongs to the TBCA family.	Centromere protein I.	0.860
GX50_01031	GX50_06342	A0A2B7ZR88	A0A2B7ZDI2	Tubulin-specific chaperone A; Belongs to the TBCA family.	Uncharacterized protein.	0.589
GX50_01031	GX50_06989	A0A2B7ZR88	A0A2B7ZA19	Tubulin-specific chaperone A; Belongs to the TBCA family.	CAP-Gly domain-containing protein.	0.815
GX50_01282	GX50_01031	A0A2B7ZH68	A0A2B7ZR88	Prefoldin subunit 2.	Tubulin-specific chaperone A; Belongs to the TBCA family.	0.579
GX50_01282	GX50_03209	A0A2B7ZH68	A0A2B7ZLU6	Prefoldin subunit 2.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.611
GX50_01282	GX50_03376	A0A2B7ZH68	A0A2B7ZLX2	Prefoldin subunit 2.	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.611

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Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.211

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016573

Histone acetylation

4 of 30

2.14

2.62

5.37e-06

GO:0045893

Positive regulation of transcription, DNA-templated

5 of 150

1.54

1.76

3.13e-05

GO:0006366

Transcription by RNA polymerase II

4 of 83

1.7

1.75

0.00011

GO:0006367

Transcription initiation from RNA polymerase II promoter

3 of 35

1.95

1.64

0.00050

GO:0006355

Regulation of transcription, DNA-templated

9 of 582

1.21

1.55

4.39e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003712

Transcription coregulator activity

7 of 64

2.06

4.29

1.32e-10

GO:0003713

Transcription coactivator activity

4 of 19

2.34

2.92

2.11e-06

GO:0046982

Protein heterodimerization activity

4 of 27

2.19

2.64

5.61e-06

GO:0017025

TBP-class protein binding

2 of 11

2.28

0.96

0.0170

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000124

SAGA complex

10 of 17

2.79

11.49

7.14e-24

GO:0005654

Nucleoplasm

11 of 201

1.76

4.81

7.92e-18

GO:1990234

Transferase complex

11 of 315

1.56

3.56

8.65e-16

GO:0140535

Intracellular protein-containing complex

11 of 348

1.52

3.32

2.26e-15

GO:0046695

SLIK (SAGA-like) complex

3 of 5

2.8

3.13

1.67e-06

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4491

SAGA complex

8 of 11

2.88

9.08

3.10e-18

CL:4495

SAGA complex

4 of 6

2.84

4.22

1.46e-08

CL:6970

Transcription factor TFIID complex

3 of 9

2.54

2.51

2.02e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03022

Basal transcription factors

3 of 57

1.74

1.2

0.0034

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5688426

Deubiquitination

4 of 94

1.65

1.3

0.0015

MAP-76042

RNA Polymerase II Transcription Initiation And Promoter Clearance

3 of 44

1.85

1.24

0.0033

MAP-75953

RNA Polymerase II Transcription Initiation

3 of 44

1.85

1.24

0.0033

MAP-73779

RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

3 of 44

1.85

1.24

0.0033

MAP-73776

RNA Polymerase II Promoter Escape

3 of 44

1.85

1.24

0.0033

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070461

SAGA-type complex

8 of 17

2.69

8.35

2.39e-17

GOCC:0000124

SAGA complex

7 of 15

2.69

7.4

2.69e-15

GOCC:0005654

Nucleoplasm

11 of 252

1.66

4.07

3.75e-16

GOCC:1990234

Transferase complex

11 of 374

1.49

3.13

9.71e-15

GOCC:0016591

RNA polymerase II, holoenzyme

3 of 39

1.9

1.66

0.00040

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR009072

Histone-fold

4 of 21

2.3

2.47

1.64e-05

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