STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GX50_004913-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)    
Predicted Functional Partners:
GX50_00490
Aa_trans domain-containing protein.
 
      0.898
GX50_08513
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 0.679
GX50_02188
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
    
  0.606
GX50_03753
Uncharacterized protein.
   
  0.603
GX50_04662
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.602
GX50_05424
Lactamase_B domain-containing protein.
   
  0.573
GX50_04939
2Fe-2S ferredoxin-type domain-containing protein.
   
  0.573
GX50_01476
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.543
GX50_05236
Uncharacterized protein.
    
  0.525
GX50_08443
Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
    
  0.490
Your Current Organism:
Emmonsia crescens
NCBI taxonomy Id: 73230
Other names: ATCC 13704, Ajellomyces crescens, CBS 177.60, Chrysosporium parvum var. crescens, E. crescens, Emmonsia parva var. crescens, UAMH 3008
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.