STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PY03601Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (507 aa)    
Predicted Functional Partners:
PY03479
GMP synthetase.
 
 0.996
PY03301
Adenylosuccinate synthetase; Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
  
 
 0.994
PY01726
Ham1 family.
  
 0.966
PY00624
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.819
PY07545
Adenylosuccinate lyase-related.
  
  
 0.813
PY05969
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.813
PY01071
Multidomain scavenger receptor protein PbSR.
   
    0.797
PY00839
Krueppel-like protein.
  
  
 0.788
PY02580
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.759
PY00264
Riboflavin kinase / FAD synthetase, putative.
     
 0.739
Your Current Organism:
Plasmodium yoelii
NCBI taxonomy Id: 73239
Other names: P. yoelii yoelii, Plasmodium yoelii subsp. yoelii, Plasmodium yoelii yoelii
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