node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | PY01116 | Q7RJM3 | Q7RQI1 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition cmplx subunit 5-related. | 0.989 |
MCM7 | PY02431 | Q7RJM3 | Q7RLV8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | MCM2/3/5 family; Belongs to the MCM family. | 0.995 |
MCM7 | PY02857 | Q7RJM3 | Q7RKP3 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor of the MCM family-related; Belongs to the MCM family. | 0.994 |
MCM7 | PY03411 | Q7RJM3 | Q7RJ52 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM4-related; Belongs to the MCM family. | 0.999 |
MCM7 | PY03736 | Q7RJM3 | Q7RI91 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Replication origin activator 2-related; Belongs to the MCM family. | 0.999 |
MCM7 | PY04668 | Q7RJM3 | Q7RFN7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM5; Belongs to the MCM family. | 0.999 |
MCM7 | PY05084 | Q7RJM3 | Q7REI0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Zf-primase domain-containing protein. | 0.998 |
MCM7 | PY05283 | Q7RJM3 | Q7RDY6 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.998 |
MCM7 | PY06659 | Q7RJM3 | Q7RA46 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | AAA domain-containing protein. | 0.989 |
MCM7 | PY06660 | Q7RJM3 | Q7RA45 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.989 |
PY01116 | MCM7 | Q7RQI1 | Q7RJM3 | Origin recognition cmplx subunit 5-related. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.989 |
PY01116 | PY02431 | Q7RQI1 | Q7RLV8 | Origin recognition cmplx subunit 5-related. | MCM2/3/5 family; Belongs to the MCM family. | 0.969 |
PY01116 | PY02857 | Q7RQI1 | Q7RKP3 | Origin recognition cmplx subunit 5-related. | DNA replication licensing factor of the MCM family-related; Belongs to the MCM family. | 0.980 |
PY01116 | PY03411 | Q7RQI1 | Q7RJ52 | Origin recognition cmplx subunit 5-related. | DNA replication licensing factor MCM4-related; Belongs to the MCM family. | 0.990 |
PY01116 | PY03736 | Q7RQI1 | Q7RI91 | Origin recognition cmplx subunit 5-related. | Replication origin activator 2-related; Belongs to the MCM family. | 0.996 |
PY01116 | PY04668 | Q7RQI1 | Q7RFN7 | Origin recognition cmplx subunit 5-related. | DNA replication licensing factor MCM5; Belongs to the MCM family. | 0.999 |
PY01116 | PY05084 | Q7RQI1 | Q7REI0 | Origin recognition cmplx subunit 5-related. | Zf-primase domain-containing protein. | 0.916 |
PY01116 | PY05283 | Q7RQI1 | Q7RDY6 | Origin recognition cmplx subunit 5-related. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |
PY01116 | PY06659 | Q7RQI1 | Q7RA46 | Origin recognition cmplx subunit 5-related. | AAA domain-containing protein. | 0.977 |
PY01116 | PY06660 | Q7RQI1 | Q7RA45 | Origin recognition cmplx subunit 5-related. | Uncharacterized protein. | 0.977 |