STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0186_00090Hydroxymethylbilane synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (248 aa)    
Predicted Functional Partners:
hemX
HemX protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.927
hemB
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.889
hemY
Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.837
hemL_3
Glutamate-1-semialdehyde 2,1-aminomutase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.650
holA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.578
lolA
Outer-membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
     0.573
trkA
Trk system potassium transport protein TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.535
ktrA
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.535
imp
LPS assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
     0.505
ccmC
Heme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
  
    0.496
Your Current Organism:
Haemophilus haemoglobinophilus
NCBI taxonomy Id: 733
Other names: ATCC 19416, Bacillus haemoglobinophilus canis, Bacterium haemoglobinophilus, CCUG 3714, CIP 53.88, DSM 21241, H. haemoglobinophilus, Hemophilus canis
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