STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lolCPermease; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)    
Predicted Functional Partners:
lolD_1
Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
 
 0.980
macB_2
Hypothetical protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.960
macB_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.954
lolE
Lipoprotein transporter subunit LolE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
0.892
lolA
Outer-membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
 
 
 0.875
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 
 0.784
yaeT
Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
   
 0.771
lolD_2
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.767
tolQ
Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
    0.681
ldhA_2
Glycerate dehydrogenase; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.534
Your Current Organism:
Haemophilus haemoglobinophilus
NCBI taxonomy Id: 733
Other names: ATCC 19416, Bacillus haemoglobinophilus canis, Bacterium haemoglobinophilus, CCUG 3714, CIP 53.88, DSM 21241, H. haemoglobinophilus, Hemophilus canis
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