STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruBBifunctional PTS fructose transporter subunit IIA/HPr protein; Phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)    
Predicted Functional Partners:
mtlA
PTS mannitol transporter subunit IICBA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIC forms the translocation channel and contains the specific substrate-binding site; subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.999
ptsI
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 0.999
fruA
PTS fructose transporter subunit EIIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
manX
PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
lacC
1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.
 
 
 0.998
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.976
crr
PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.955
ptsB
PTS maltose transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.923
ptsEII
PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.923
ptsN
PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.889
Your Current Organism:
Haemophilus haemoglobinophilus
NCBI taxonomy Id: 733
Other names: ATCC 19416, Bacillus haemoglobinophilus canis, Bacterium haemoglobinophilus, CCUG 3714, CIP 53.88, DSM 21241, H. haemoglobinophilus, Hemophilus canis
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