STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsrAMFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. (462 aa)    
Predicted Functional Partners:
mobB
Molybdopterin-guanine dinucleotide biosynthesis protein B; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.792
rseB
sigma-E factor regulatory protein RseB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.762
rseC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.762
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
       0.757
pheA
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.699
tyrA
Bifunctional chorismate mutase/prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.593
rseA
Transcriptional regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish d [...]
       0.566
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
       0.550
rpoE_1
RNA polymerase sigma factor RpoE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.502
ttgC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.480
Your Current Organism:
Haemophilus haemoglobinophilus
NCBI taxonomy Id: 733
Other names: ATCC 19416, Bacillus haemoglobinophilus canis, Bacterium haemoglobinophilus, CCUG 3714, CIP 53.88, DSM 21241, H. haemoglobinophilus, Hemophilus canis
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.