Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppcHypothetical protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (879 aa)    
Predicted Functional Partners:
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.962
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
     
 0.936
pgk
Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family.
  
 
 0.935
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 
 0.933
OOS00137.1
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
     
 0.929
OOS00614.1
Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
     
 0.927
OOS00755.1
Oxaloacetate decarboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.926
OOR99128.1
Formate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
     
 0.906
OOR99127.1
Formate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.905
gpmA
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
     
 0.905
Your Current Organism:
Haemophilus paracuniculus
NCBI taxonomy Id: 734
Other names: ATCC 29986, CCUG 43573, CIP 107045, DSM 21452, H. paracuniculus
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