Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lolAOuter membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (208 aa)    
Predicted Functional Partners:
lolB
Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
 
 
 0.961
lolD
Lipoprotein ABC transporter ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
   
 
 0.925
OOR95174.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.798
LolE
Lipoprotein transporter subunit LolE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.782
lptD
LPS assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
   
 0.759
bamA
Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
   
 0.737
lptF
LPS export ABC transporter permease LptF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.660
dsbA_1
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.658
trpR
Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
 
     0.635
HolA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.633
Your Current Organism:
Haemophilus parahaemolyticus
NCBI taxonomy Id: 735
Other names: ATCC 10014, CCUG 3716, CIP 56.86, DSM 21417, H. parahaemolyticus, NCTC 8479
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.