Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (113 aa)    
Predicted Functional Partners:
iscS
IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
 
 0.749
iscU
Iron-sulfur cluster scaffold-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.739
nfuA
Fe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
 
 
 0.708
OOR96865.1
Folate-binding protein YgfZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
 
 
 0.618
grxD
Monothiol glutaredoxin, Grx4 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.548
OOR96706.1
Chain-length determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
OOR96707.1
Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
OOR96708.1
Glycosyl transferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
OOR96709.1
Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
OOR96710.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.501
Your Current Organism:
Haemophilus parahaemolyticus
NCBI taxonomy Id: 735
Other names: ATCC 10014, CCUG 3716, CIP 56.86, DSM 21417, H. parahaemolyticus, NCTC 8479
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