node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | guaA | B0184_08560 | B0184_07420 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphatase; Catalyzes the synthesis of GMP from XMP. | 0.985 |
argS | lepA | B0184_08560 | B0184_06845 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.611 |
argS | metG | B0184_08560 | B0184_00175 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.957 |
argS | pheT | B0184_08560 | B0184_07260 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.818 |
argS | prfA | B0184_08560 | B0184_02360 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.528 |
argS | pyrG | B0184_08560 | B0184_02035 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.697 |
argS | rpsG | B0184_08560 | B0184_04550 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.707 |
argS | ychF | B0184_08560 | B0184_00005 | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.643 |
guaA | argS | B0184_07420 | B0184_08560 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
guaA | lepA | B0184_07420 | B0184_06845 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.535 |
guaA | metG | B0184_07420 | B0184_00175 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.819 |
guaA | pheT | B0184_07420 | B0184_07260 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.892 |
guaA | pth | B0184_07420 | B0184_09495 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.574 |
guaA | pyrG | B0184_07420 | B0184_02035 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.979 |
guaA | rpsG | B0184_07420 | B0184_04550 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.660 |
guaA | topA | B0184_07420 | B0184_07535 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.479 |
guaA | ychF | B0184_07420 | B0184_00005 | Phosphatase; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.754 |
lepA | argS | B0184_06845 | B0184_08560 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.611 |
lepA | guaA | B0184_06845 | B0184_07420 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Phosphatase; Catalyzes the synthesis of GMP from XMP. | 0.535 |
lepA | metG | B0184_06845 | B0184_00175 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.433 |