Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
cpdAPhosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (279 aa)    
Predicted Functional Partners:
OOR94743.1
Nucleoside triphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.934
OOR94617.1
Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.922
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.918
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.918
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
  0.918
guaA
Phosphatase; Catalyzes the synthesis of GMP from XMP.
    
 0.728
OOR95119.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.718
OOR95209.1
Transcriptional regulator Crp; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.640
OOR96289.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.538
OOR94868.1
SH3 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.502
Your Current Organism:
Haemophilus paraphrohaemolyticus
NCBI taxonomy Id: 736
Other names: ATCC 29237, CCUG 3718, CIP 102512, DSM 21451, H. paraphrohaemolyticus, NCTC 10670
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