Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
OOR96411.1Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)    
Predicted Functional Partners:
nrfF
Cytochrome C biosynthesis protein; Possible subunit of a heme lyase.
 
  
 0.950
nrfE
Heme lyase CcmF/NrfE family subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.932
msrA
Peptide-methionine (R)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.910
OOR96413.1
Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.896
OOR96631.1
Cytochrome c-type biogenesis protein; required for the transfer of heme to apocytochrome c; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.879
ccmC
Heme ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.861
ccmE
Cytochrome c biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
  
 0.859
OOR95982.1
Cytochrome c-type biogenesis protein CcmH; Possible subunit of a heme lyase.
 
  
 0.859
ccmI
C-type cytochrome biogenesis protein CcmI; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.816
ccmB
Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
  
 0.796
Your Current Organism:
Haemophilus paraphrohaemolyticus
NCBI taxonomy Id: 736
Other names: ATCC 29237, CCUG 3718, CIP 102512, DSM 21451, H. paraphrohaemolyticus, NCTC 10670
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