Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trmAtRNA (uridine(54)-C5)-methyltransferase TrmA; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). (369 aa)    
Predicted Functional Partners:
OOR95206.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.625
OOR94922.1
YcgL domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.513
OOR94397.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.504
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
     0.495
OOR95205.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.473
sixA
Phosphohistidine phosphatase SixA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.456
OOR95208.1
Rossman fold protein, TIGR00730 family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.
       0.420
Your Current Organism:
Haemophilus paraphrohaemolyticus
NCBI taxonomy Id: 736
Other names: ATCC 29237, CCUG 3718, CIP 102512, DSM 21451, H. paraphrohaemolyticus, NCTC 10670
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