Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdxHFormate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (307 aa)    
Predicted Functional Partners:
fdnG
Formate dehydrogenase-N subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 0.999
OOR94612.1
Formate dehydrogenase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
OOR94609.1
Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
fdhE
Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
  
 0.925
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.923
OOR96184.1
Malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.918
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
  0.918
fumC
Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.918
OOR94935.1
Oxaloacetate decarboxylase subunit beta; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family.
     
  0.918
oadA
Oxaloacetate decarboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.918
Your Current Organism:
Haemophilus paraphrohaemolyticus
NCBI taxonomy Id: 736
Other names: ATCC 29237, CCUG 3718, CIP 102512, DSM 21451, H. paraphrohaemolyticus, NCTC 10670
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