Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
OOR93042.1Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (293 aa)    
Predicted Functional Partners:
exbD
TonB system transport protein ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
exbB
TonB-system energizer ExbB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
OOR95825.1
Iron-regulated outer membrane virulence protein; Iron-responsive element (ireA); ireA gene is located on pathogenicity island I (PAI I); outer membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.950
tolR
Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.920
tolQ
Tol-Pal system subunit TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.886
OOR94393.1
Cobalamin receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.872
OOR96137.1
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.864
B0184_01945
Acylphosphatase; Catalyzes the hydrolysis of acylphosphate; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.852
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.818
OOR94604.1
Ligand-gated channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.793
Your Current Organism:
Haemophilus paraphrohaemolyticus
NCBI taxonomy Id: 736
Other names: ATCC 29237, CCUG 3718, CIP 102512, DSM 21451, H. paraphrohaemolyticus, NCTC 10670
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