STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mdmd-2Male determiner protein Mdmd(Y); Male determiner protein (M-factor) that controls male somatic sexual differentiation. Acts as a dominant factor that regulates the mRNA splicing of transformer (tra) and doublesex (dsx) transcripts and promotes expression of male splice forms of tra and dsx (By similarity). Probably acts as a component of the spliceosome C complex required for mRNA splicing factor and exon-junction complex (EJC) assembly (By similarity). Hinders eIF4AIII from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs (B [...] (1174 aa)    
Predicted Functional Partners:
A0A1I8MP00
PPIase cyclophilin-type domain-containing protein.
   
 0.895
A0A1I8MTI7
Slu7 domain-containing protein.
   
 0.883
A0A1I8NFZ0
WD_REPEATS_REGION domain-containing protein.
   
 0.861
T1PG03_MUSDO
DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
    
 0.861
A0A1I8M514
Uncharacterized protein.
    
 0.859
A0A1I8MKQ5
Cir_N domain-containing protein.
   
 0.854
A0A1I8MP48
Uncharacterized protein.
    
 0.852
A0A1I8MQL1
Cwf21 domain-containing protein.
    
 0.849
A0A1I8N6A3
Uncharacterized protein.
   
 
 0.828
A0A1I8M786
Uncharacterized protein.
   
 
 0.824
Your Current Organism:
Musca domestica
NCBI taxonomy Id: 7370
Other names: house fly
Server load: low (20%) [HD]