STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T1PC58_MUSDOPX domain protein. (167 aa)    
Predicted Functional Partners:
A0A1I8MT54
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.989
A0A1I8MNP2
Uncharacterized protein.
    
 0.966
A0A1I8N5V9
VWFA domain-containing protein.
    
 0.923
A0A1I8M6W1
Uncharacterized protein.
    
 0.917
T1PDZ6_MUSDO
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 0.905
A0A1I8MLZ7
PX domain-containing protein.
   
 
0.728
A0A1I8MHY2
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
    
 
 0.723
T1P8L1_MUSDO
PX domain protein.
    
 
 0.722
A0A1I8MBA4
PX domain-containing protein.
   
 
 0.717
A0A1I8M0W1
USP domain-containing protein; Belongs to the peptidase C19 family.
    
 0.716
Your Current Organism:
Musca domestica
NCBI taxonomy Id: 7370
Other names: house fly
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