STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y3NQQ2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (294 aa)    
Predicted Functional Partners:
A0A1Y3NFA4
Uncharacterized protein.
  
 0.953
A0A1Y3NKM2
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.909
A0A1Y3N7A3
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 0.840
A0A1Y3NG70
Pribosyltran domain-containing protein.
  
 
 0.840
A0A1Y3N611
Tr-type G domain-containing protein.
  
 0.836
A0A1Y3MSI9
Uncharacterized protein.
  
 
 0.825
A0A1Y3MSJ4
Uncharacterized protein.
  
 
 0.825
A0A1Y3NPE3
Pribosyltran domain-containing protein.
    
 0.809
A0A1Y3MX10
Glutamine amidotransferase type-1 domain-containing protein.
  
 
 0.791
A0A1Y3NIV7
Guanylate kinase-like domain-containing protein.
  
 
 0.791
Your Current Organism:
Piromyces sp. E2
NCBI taxonomy Id: 73868
Other names: P. sp. E2
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