node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dksA | folK | GCA_001059425_01228 | GCA_001059425_01226 | Unannotated protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Unannotated protein. | 0.511 |
dksA | pcnB | GCA_001059425_01228 | GCA_001059425_01227 | Unannotated protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Unannotated protein; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.511 |
folB | folC | GCA_001059425_00832 | GCA_001059425_01182 | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Unannotated protein; Belongs to the folylpolyglutamate synthase family. | 0.543 |
folB | folE | GCA_001059425_00832 | GCA_001059425_01217 | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Unannotated protein. | 0.887 |
folB | folK | GCA_001059425_00832 | GCA_001059425_01226 | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Unannotated protein. | 0.970 |
folB | folP | GCA_001059425_00832 | GCA_001059425_00954 | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.992 |
folB | ribD | GCA_001059425_00832 | GCA_001059425_00729 | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.596 |
folC | folB | GCA_001059425_01182 | GCA_001059425_00832 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.543 |
folC | folE | GCA_001059425_01182 | GCA_001059425_01217 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. | Unannotated protein. | 0.619 |
folC | folK | GCA_001059425_01182 | GCA_001059425_01226 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. | Unannotated protein. | 0.623 |
folC | folP | GCA_001059425_01182 | GCA_001059425_00954 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. | Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.983 |
folC | ribD | GCA_001059425_01182 | GCA_001059425_00729 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.555 |
folE | folB | GCA_001059425_01217 | GCA_001059425_00832 | Unannotated protein. | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.887 |
folE | folC | GCA_001059425_01217 | GCA_001059425_01182 | Unannotated protein. | Unannotated protein; Belongs to the folylpolyglutamate synthase family. | 0.619 |
folE | folK | GCA_001059425_01217 | GCA_001059425_01226 | Unannotated protein. | Unannotated protein. | 0.979 |
folE | folP | GCA_001059425_01217 | GCA_001059425_00954 | Unannotated protein. | Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.921 |
folE | rdgB | GCA_001059425_01217 | GCA_001059425_01580 | Unannotated protein. | Unannotated protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.482 |
folE | ribD | GCA_001059425_01217 | GCA_001059425_00729 | Unannotated protein. | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.559 |
folK | dksA | GCA_001059425_01226 | GCA_001059425_01228 | Unannotated protein. | Unannotated protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.511 |
folK | folB | GCA_001059425_01226 | GCA_001059425_00832 | Unannotated protein. | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.970 |