STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
surEUnannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (246 aa)    
Predicted Functional Partners:
guaA
Unannotated protein; Catalyzes the synthesis of GMP from XMP.
    
 0.955
guaB
Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.945
pyrH
Unannotated protein; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.938
truD
Unannotated protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
  
 0.933
purH
Unannotated protein.
     
 0.926
adk
Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.919
upp2
Unannotated protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.919
cdd
Unannotated protein; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
  
  
 0.918
purB
Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.916
cmk
Unannotated protein.
    
 0.916
Your Current Organism:
Aggregatibacter segnis
NCBI taxonomy Id: 739
Other names: A. segnis, ATCC 33393, CCUG 10787, CCUG 12838, CIP 103292, DSM 21418, Haemophilus segnis, NCTC 10977, strain HK 316, strain HK316
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.