node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEM36274.1 | asnC_2 | SAMN04488077_10490 | SAMN04488077_10492 | Aspartate aminotransferase. | Transcriptional regulator, AsnC family. | 0.696 |
SEM36274.1 | ilvC | SAMN04488077_10490 | SAMN04488077_10493 | Aspartate aminotransferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.567 |
SEM36274.1 | lrp_5 | SAMN04488077_10490 | SAMN04488077_10491 | Aspartate aminotransferase. | Transcriptional regulator, AsnC family. | 0.697 |
asnC_2 | SEM36274.1 | SAMN04488077_10492 | SAMN04488077_10490 | Transcriptional regulator, AsnC family. | Aspartate aminotransferase. | 0.696 |
asnC_2 | ilvC | SAMN04488077_10492 | SAMN04488077_10493 | Transcriptional regulator, AsnC family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.692 |
asnC_2 | lrp_5 | SAMN04488077_10492 | SAMN04488077_10491 | Transcriptional regulator, AsnC family. | Transcriptional regulator, AsnC family. | 0.874 |
asnC_2 | nasF | SAMN04488077_10492 | SAMN04488077_101294 | Transcriptional regulator, AsnC family. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.545 |
ilvC | SEM36274.1 | SAMN04488077_10493 | SAMN04488077_10490 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Aspartate aminotransferase. | 0.567 |
ilvC | asnC_2 | SAMN04488077_10493 | SAMN04488077_10492 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Transcriptional regulator, AsnC family. | 0.692 |
ilvC | lrp_5 | SAMN04488077_10493 | SAMN04488077_10491 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Transcriptional regulator, AsnC family. | 0.692 |
ilvC | nasF | SAMN04488077_10493 | SAMN04488077_101294 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.408 |
lrp_5 | SEM36274.1 | SAMN04488077_10491 | SAMN04488077_10490 | Transcriptional regulator, AsnC family. | Aspartate aminotransferase. | 0.697 |
lrp_5 | asnC_2 | SAMN04488077_10491 | SAMN04488077_10492 | Transcriptional regulator, AsnC family. | Transcriptional regulator, AsnC family. | 0.874 |
lrp_5 | ilvC | SAMN04488077_10491 | SAMN04488077_10493 | Transcriptional regulator, AsnC family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.692 |
lrp_5 | nasF | SAMN04488077_10491 | SAMN04488077_101294 | Transcriptional regulator, AsnC family. | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.545 |
nasF | asnC_2 | SAMN04488077_101294 | SAMN04488077_10492 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Transcriptional regulator, AsnC family. | 0.545 |
nasF | ilvC | SAMN04488077_101294 | SAMN04488077_10493 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.408 |
nasF | lrp_5 | SAMN04488077_101294 | SAMN04488077_10491 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Transcriptional regulator, AsnC family. | 0.545 |