STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsICell division protein FtsI (penicillin-binding protein 3). (594 aa)    
Predicted Functional Partners:
ftsW
Cell division protein FtsW; Belongs to the SEDS family.
 
 0.994
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
 0.992
mrdB
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.988
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
 
 
 0.983
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
 0.976
pbpG_2
Penicillin-binding protein, 1A family.
 
 
0.966
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
 0.963
spoVD
Peptidoglycan glycosyltransferase.
 
  
0.954
rsmH
16S rRNA (cytosine1402-N4)-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
 0.947
mraZ
MraZ protein; Belongs to the MraZ family.
 
  
 0.933
Your Current Organism:
Roseovarius tolerans
NCBI taxonomy Id: 74031
Other names: CIP 106398, DSM 11457, IFO 16695, JCM 21346, NBRC 16695, R. tolerans, strain EL-172
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.