STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEN83089.1Adenylate cyclase. (507 aa)    
Predicted Functional Partners:
SEN31213.1
GAF domain-containing protein.
  
 
 0.971
ribBA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.935
mazG
ATP diphosphatase.
  
 
  0.860
ttuE
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.859
moaA_1
Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
 
 0.857
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.854
rsh
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
  0.850
divJ
Signal transduction histidine kinase.
  
 
 0.833
nasF
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
    
 0.794
SEN35981.1
TolB amino-terminal domain-containing protein.
 
  
0.756
Your Current Organism:
Roseovarius tolerans
NCBI taxonomy Id: 74031
Other names: CIP 106398, DSM 11457, IFO 16695, JCM 21346, NBRC 16695, R. tolerans, strain EL-172
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.