STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKE80599.1uroporphyrin-III C-methyltransferase; COG2959 Uncharacterized enzyme of heme biosynthesis. (396 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.998
EKE80598.1
Hypothetical protein; COG3071 Uncharacterized enzyme of heme biosynthesis.
 
  
 0.985
EKE80600.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 
 0.961
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.906
EKE84476.1
COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 0.872
cyaY
Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
       0.794
EKE87555.1
Hypothetical protein.
   
 
 0.781
EKE86965.1
COG0778 Nitroreductase.
   
 
 0.781
EKE87550.1
Hypothetical protein.
   
 
 0.739
EKE84799.1
COG1694 Predicted pyrophosphatase.
    
  0.726
Your Current Organism:
Idiomarina xiamenensis
NCBI taxonomy Id: 740709
Other names: I. xiamenensis 10-D-4, Idiomarina sp. 10-D-4, Idiomarina xiamenensis 10-D-4, Idiomarina xiamenensis str. 10-D-4, Idiomarina xiamenensis strain 10-D-4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.