Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
UYA_01020DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (799 aa)    
Predicted Functional Partners:
UYA_01025
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
UYA_01035
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.989
UYA_23395
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.952
UYA_23405
Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.892
UYA_01030
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.873
UYA_10945
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.718
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.499
UYA_01015
Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.478
UYA_17755
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.465
UYA_12420
ATP-dependent endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.426
Your Current Organism:
Pseudomonas alcaliphila
NCBI taxonomy Id: 741155
Other names: P. alcaliphila JAB1, Pseudomonas alcaliphila JAB1, Pseudomonas alcaliphila str. JAB1, Pseudomonas alcaliphila strain JAB1, Pseudomonas sp. JAB1
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