Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureDUrease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (278 aa)    
Predicted Functional Partners:
ureB
Urease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family.
 
 
 0.995
ureA
Urease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family.
 
 
 0.994
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.992
ureC
Urease subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.976
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
 
 0.959
UYA_03325
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.847
UYA_03405
Urea ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.658
UYA_02535
Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.640
UYA_03160
Protein hupE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.639
Your Current Organism:
Pseudomonas alcaliphila
NCBI taxonomy Id: 741155
Other names: P. alcaliphila JAB1, Pseudomonas alcaliphila JAB1, Pseudomonas alcaliphila str. JAB1, Pseudomonas alcaliphila strain JAB1, Pseudomonas sp. JAB1
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