STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lptALipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (179 aa)    
Predicted Functional Partners:
lptC
LPS export ABC transporter periplasmic protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
 
 
 0.993
UYA_04260
LPS export ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.976
lptD
LPS biosynthesis protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
 
 0.908
UYA_04275
Phenylphosphate carboxylase subunit delta; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.
  
  
 0.843
UYA_04280
D-arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.831
UYA_04300
Toluene tolerance protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.772
bamE
Hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.692
bamA
Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
  
 0.679
UYA_04305
Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.678
UYA_04255
RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.641
Your Current Organism:
Pseudomonas alcaliphila
NCBI taxonomy Id: 741155
Other names: P. alcaliphila JAB1, Pseudomonas alcaliphila JAB1, Pseudomonas alcaliphila str. JAB1, Pseudomonas alcaliphila strain JAB1, Pseudomonas sp. JAB1
Server load: low (14%) [HD]