STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UYA_15555Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)    
Predicted Functional Partners:
msrB
Peptide-methionine (R)-S-oxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MsrB Met sulfoxide reductase family.
  
    0.932
UYA_15550
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.842
UYA_15560
Rhomboid family intramembrane serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.800
UYA_13180
Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
    0.776
UYA_14305
Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.754
UYA_23910
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.728
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.724
UYA_15565
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.711
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
     0.685
UYA_08320
ApbE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.680
Your Current Organism:
Pseudomonas alcaliphila
NCBI taxonomy Id: 741155
Other names: P. alcaliphila JAB1, Pseudomonas alcaliphila JAB1, Pseudomonas alcaliphila str. JAB1, Pseudomonas alcaliphila strain JAB1, Pseudomonas sp. JAB1
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