node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGG81834.1 | EGG84851.1 | HMPREF9477_01536 | HMPREF9477_00578 | Hypothetical protein; Belongs to the DEAD box helicase family. | Small GTP-binding protein domain protein. | 0.911 |
EGG81834.1 | efp | HMPREF9477_01536 | HMPREF9477_00798 | Hypothetical protein; Belongs to the DEAD box helicase family. | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.471 |
EGG81834.1 | rplA | HMPREF9477_01536 | HMPREF9477_01375 | Hypothetical protein; Belongs to the DEAD box helicase family. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.731 |
EGG81834.1 | rplB | HMPREF9477_01536 | HMPREF9477_01141 | Hypothetical protein; Belongs to the DEAD box helicase family. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.718 |
EGG81834.1 | rplF | HMPREF9477_01536 | HMPREF9477_01129 | Hypothetical protein; Belongs to the DEAD box helicase family. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.672 |
EGG81834.1 | rplJ | HMPREF9477_01536 | HMPREF9477_01373 | Hypothetical protein; Belongs to the DEAD box helicase family. | Hypothetical protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.768 |
EGG81834.1 | rplK | HMPREF9477_01536 | HMPREF9477_01376 | Hypothetical protein; Belongs to the DEAD box helicase family. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.758 |
EGG81834.1 | rpsG | HMPREF9477_01536 | HMPREF9477_01335 | Hypothetical protein; Belongs to the DEAD box helicase family. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.680 |
EGG81834.1 | rpsL | HMPREF9477_01536 | HMPREF9477_01336 | Hypothetical protein; Belongs to the DEAD box helicase family. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.704 |
EGG84851.1 | EGG81834.1 | HMPREF9477_00578 | HMPREF9477_01536 | Small GTP-binding protein domain protein. | Hypothetical protein; Belongs to the DEAD box helicase family. | 0.911 |
EGG84851.1 | efp | HMPREF9477_00578 | HMPREF9477_00798 | Small GTP-binding protein domain protein. | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.872 |
EGG84851.1 | rplA | HMPREF9477_00578 | HMPREF9477_01375 | Small GTP-binding protein domain protein. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.884 |
EGG84851.1 | rplB | HMPREF9477_00578 | HMPREF9477_01141 | Small GTP-binding protein domain protein. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.882 |
EGG84851.1 | rplF | HMPREF9477_00578 | HMPREF9477_01129 | Small GTP-binding protein domain protein. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.877 |
EGG84851.1 | rplJ | HMPREF9477_00578 | HMPREF9477_01373 | Small GTP-binding protein domain protein. | Hypothetical protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.872 |
EGG84851.1 | rplK | HMPREF9477_00578 | HMPREF9477_01376 | Small GTP-binding protein domain protein. | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.874 |
EGG84851.1 | rpsG | HMPREF9477_00578 | HMPREF9477_01335 | Small GTP-binding protein domain protein. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.888 |
EGG84851.1 | rpsL | HMPREF9477_00578 | HMPREF9477_01336 | Small GTP-binding protein domain protein. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.884 |
EGG84851.1 | tuf | HMPREF9477_00578 | HMPREF9477_01333 | Small GTP-binding protein domain protein. | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.870 |
efp | EGG81834.1 | HMPREF9477_00798 | HMPREF9477_01536 | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Hypothetical protein; Belongs to the DEAD box helicase family. | 0.471 |