| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJZ62065.1 | EJZ62508.1 | HMPREF9448_02746 | HMPREF9448_02423 | KpsF/GutQ family sugar isomerase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.743 |
| EJZ62065.1 | EJZ62747.1 | HMPREF9448_02746 | HMPREF9448_02098 | KpsF/GutQ family sugar isomerase. | Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.779 |
| EJZ62065.1 | EJZ62846.1 | HMPREF9448_02746 | HMPREF9448_02198 | KpsF/GutQ family sugar isomerase. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.936 |
| EJZ62065.1 | EJZ62961.1 | HMPREF9448_02746 | HMPREF9448_02315 | KpsF/GutQ family sugar isomerase. | Hypothetical protein. | 0.458 |
| EJZ62065.1 | EJZ64686.1 | HMPREF9448_02746 | HMPREF9448_01168 | KpsF/GutQ family sugar isomerase. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.624 |
| EJZ62065.1 | EJZ64857.1 | HMPREF9448_02746 | HMPREF9448_01343 | KpsF/GutQ family sugar isomerase. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase. | 0.657 |
| EJZ62065.1 | kdsB | HMPREF9448_02746 | HMPREF9448_00673 | KpsF/GutQ family sugar isomerase. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.844 |
| EJZ62065.1 | lpxD | HMPREF9448_02746 | HMPREF9448_01170 | KpsF/GutQ family sugar isomerase. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.710 |
| EJZ62065.1 | lpxK | HMPREF9448_02746 | HMPREF9448_00101 | KpsF/GutQ family sugar isomerase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.774 |
| EJZ62508.1 | EJZ62065.1 | HMPREF9448_02423 | HMPREF9448_02746 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | KpsF/GutQ family sugar isomerase. | 0.743 |
| EJZ62508.1 | EJZ62747.1 | HMPREF9448_02423 | HMPREF9448_02098 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.826 |
| EJZ62508.1 | EJZ62846.1 | HMPREF9448_02423 | HMPREF9448_02198 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. | 0.792 |
| EJZ62508.1 | EJZ62961.1 | HMPREF9448_02423 | HMPREF9448_02315 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Hypothetical protein. | 0.828 |
| EJZ62508.1 | EJZ64686.1 | HMPREF9448_02423 | HMPREF9448_01168 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.945 |
| EJZ62508.1 | EJZ64857.1 | HMPREF9448_02423 | HMPREF9448_01343 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase. | 0.945 |
| EJZ62508.1 | kdsB | HMPREF9448_02423 | HMPREF9448_00673 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.820 |
| EJZ62508.1 | lpxD | HMPREF9448_02423 | HMPREF9448_01170 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.941 |
| EJZ62508.1 | lpxK | HMPREF9448_02423 | HMPREF9448_00101 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.932 |
| EJZ62747.1 | EJZ62065.1 | HMPREF9448_02098 | HMPREF9448_02746 | Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | KpsF/GutQ family sugar isomerase. | 0.779 |
| EJZ62747.1 | EJZ62508.1 | HMPREF9448_02098 | HMPREF9448_02423 | Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.826 |