| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJZ62894.1 | EJZ65896.1 | HMPREF9448_02248 | HMPREF9448_00066 | biotin-[acetyl-CoA-carboxylase] ligase. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.668 |
| EJZ62894.1 | coaD | HMPREF9448_02248 | HMPREF9448_02517 | biotin-[acetyl-CoA-carboxylase] ligase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.646 |
| EJZ62894.1 | coaX | HMPREF9448_02248 | HMPREF9448_00529 | biotin-[acetyl-CoA-carboxylase] ligase. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.410 |
| EJZ62894.1 | panC | HMPREF9448_02248 | HMPREF9448_01290 | biotin-[acetyl-CoA-carboxylase] ligase. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.736 |
| EJZ64259.1 | cmk | HMPREF9448_01519 | HMPREF9448_00764 | MazG family protein. | Cytidylate kinase. | 0.656 |
| EJZ64259.1 | coaX | HMPREF9448_01519 | HMPREF9448_00529 | MazG family protein. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.609 |
| EJZ65162.1 | coaD | HMPREF9448_00893 | HMPREF9448_02517 | Hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.600 |
| EJZ65162.1 | coaX | HMPREF9448_00893 | HMPREF9448_00529 | Hypothetical protein. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.584 |
| EJZ65896.1 | EJZ62894.1 | HMPREF9448_00066 | HMPREF9448_02248 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | biotin-[acetyl-CoA-carboxylase] ligase. | 0.668 |
| EJZ65896.1 | cmk | HMPREF9448_00066 | HMPREF9448_00764 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cytidylate kinase. | 0.690 |
| EJZ65896.1 | coaD | HMPREF9448_00066 | HMPREF9448_02517 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.762 |
| EJZ65896.1 | coaX | HMPREF9448_00066 | HMPREF9448_00529 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.683 |
| EJZ65896.1 | panC | HMPREF9448_00066 | HMPREF9448_01290 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.750 |
| EJZ65896.1 | panD | HMPREF9448_00066 | HMPREF9448_01289 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.485 |
| EJZ66353.1 | coaX | HMPREF9448_00530 | HMPREF9448_00529 | Hypothetical protein. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.791 |
| cmk | EJZ64259.1 | HMPREF9448_00764 | HMPREF9448_01519 | Cytidylate kinase. | MazG family protein. | 0.656 |
| cmk | EJZ65896.1 | HMPREF9448_00764 | HMPREF9448_00066 | Cytidylate kinase. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.690 |
| cmk | coaD | HMPREF9448_00764 | HMPREF9448_02517 | Cytidylate kinase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.464 |
| cmk | coaX | HMPREF9448_00764 | HMPREF9448_00529 | Cytidylate kinase. | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.679 |
| cmk | panC | HMPREF9448_00764 | HMPREF9448_01290 | Cytidylate kinase. | Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.927 |