| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJZ62006.1 | menA | HMPREF9448_02686 | HMPREF9448_00978 | Hypothetical protein; Belongs to the FPP/GGPP synthase family. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.655 |
| EJZ62006.1 | menG | HMPREF9448_02686 | HMPREF9448_00709 | Hypothetical protein; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.646 |
| EJZ64549.1 | EJZ66207.1 | HMPREF9448_01027 | HMPREF9448_00384 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoserine phosphatase SerB. | 0.760 |
| EJZ64549.1 | menG | HMPREF9448_01027 | HMPREF9448_00709 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.640 |
| EJZ66207.1 | EJZ64549.1 | HMPREF9448_00384 | HMPREF9448_01027 | Phosphoserine phosphatase SerB. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.760 |
| EJZ66207.1 | EJZ66307.1 | HMPREF9448_00384 | HMPREF9448_00484 | Phosphoserine phosphatase SerB. | CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.687 |
| EJZ66207.1 | menG | HMPREF9448_00384 | HMPREF9448_00709 | Phosphoserine phosphatase SerB. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.665 |
| EJZ66307.1 | EJZ66207.1 | HMPREF9448_00484 | HMPREF9448_00384 | CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphoserine phosphatase SerB. | 0.687 |
| EJZ66307.1 | menG | HMPREF9448_00484 | HMPREF9448_00709 | CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.596 |
| EJZ66307.1 | psd | HMPREF9448_00484 | HMPREF9448_00483 | CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.991 |
| EJZ66422.1 | menG | HMPREF9448_00600 | HMPREF9448_00709 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.685 |
| EJZ66533.1 | menG | HMPREF9448_00712 | HMPREF9448_00709 | Hypothetical protein. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.459 |
| EJZ66533.1 | purC | HMPREF9448_00712 | HMPREF9448_00710 | Hypothetical protein. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.491 |
| bioB | menG | HMPREF9448_01147 | HMPREF9448_00709 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.471 |
| menA | EJZ62006.1 | HMPREF9448_00978 | HMPREF9448_02686 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Hypothetical protein; Belongs to the FPP/GGPP synthase family. | 0.655 |
| menA | menG | HMPREF9448_00978 | HMPREF9448_00709 | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.829 |
| menG | EJZ62006.1 | HMPREF9448_00709 | HMPREF9448_02686 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | Hypothetical protein; Belongs to the FPP/GGPP synthase family. | 0.646 |
| menG | EJZ64549.1 | HMPREF9448_00709 | HMPREF9448_01027 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.640 |
| menG | EJZ66207.1 | HMPREF9448_00709 | HMPREF9448_00384 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | Phosphoserine phosphatase SerB. | 0.665 |
| menG | EJZ66307.1 | HMPREF9448_00709 | HMPREF9448_00484 | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.596 |