| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJZ62146.1 | ftsH | HMPREF9448_02829 | HMPREF9448_02067 | serine-tRNA ligase. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.575 |
| EJZ62146.1 | ftsY | HMPREF9448_02829 | HMPREF9448_01304 | serine-tRNA ligase. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.455 |
| EJZ62146.1 | pheS | HMPREF9448_02829 | HMPREF9448_01510 | serine-tRNA ligase. | phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.833 |
| EJZ62146.1 | tsaD | HMPREF9448_02829 | HMPREF9448_01299 | serine-tRNA ligase. | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.569 |
| EJZ63872.1 | EJZ65643.1 | HMPREF9448_01711 | HMPREF9448_00730 | Universal bacterial protein YeaZ. | YjeE family ATPase. | 0.951 |
| EJZ63872.1 | tsaD | HMPREF9448_01711 | HMPREF9448_01299 | Universal bacterial protein YeaZ. | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.943 |
| EJZ64814.1 | ftsY | HMPREF9448_01300 | HMPREF9448_01304 | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.406 |
| EJZ64814.1 | tsaD | HMPREF9448_01300 | HMPREF9448_01299 | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.781 |
| EJZ65643.1 | EJZ63872.1 | HMPREF9448_00730 | HMPREF9448_01711 | YjeE family ATPase. | Universal bacterial protein YeaZ. | 0.951 |
| EJZ65643.1 | tsaD | HMPREF9448_00730 | HMPREF9448_01299 | YjeE family ATPase. | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.893 |
| EJZ65655.1 | tsaD | HMPREF9448_00742 | HMPREF9448_01299 | Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.585 |
| EJZ66235.1 | tsaD | HMPREF9448_00412 | HMPREF9448_01299 | Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.641 |
| ftsH | EJZ62146.1 | HMPREF9448_02067 | HMPREF9448_02829 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | serine-tRNA ligase. | 0.575 |
| ftsH | tsaD | HMPREF9448_02067 | HMPREF9448_01299 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.564 |
| ftsY | EJZ62146.1 | HMPREF9448_01304 | HMPREF9448_02829 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | serine-tRNA ligase. | 0.455 |
| ftsY | EJZ64814.1 | HMPREF9448_01304 | HMPREF9448_01300 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | 0.406 |
| ftsY | tsaD | HMPREF9448_01304 | HMPREF9448_01299 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.609 |
| lolD | pheS | HMPREF9448_02573 | HMPREF9448_01510 | Hypothetical protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.477 |
| lolD | tsaD | HMPREF9448_02573 | HMPREF9448_01299 | Hypothetical protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | glycoprotease/Kae1 family metallohydrolase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.652 |
| pheS | EJZ62146.1 | HMPREF9448_01510 | HMPREF9448_02829 | phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | serine-tRNA ligase. | 0.833 |