STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJZ62403.1Hypothetical protein. (348 aa)    
Predicted Functional Partners:
EJZ62399.1
Hypothetical protein.
   
 
 0.727
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.676
EJZ62902.1
Hypothetical protein.
 
 
 
 0.657
EJZ62129.1
Hypothetical protein.
   
   0.643
EJZ62843.1
Hypothetical protein.
   
 
 0.608
EJZ63759.1
Hypothetical protein.
   
 
 0.600
EJZ65989.1
Hypothetical protein.
  
   0.583
EJZ62026.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
  0.571
EJZ64259.1
MazG family protein.
    
  0.464
EJZ61905.1
Anaerobic ribonucleoside-triphosphate reductase.
    
  0.464
Your Current Organism:
Barnesiella intestinihominis
NCBI taxonomy Id: 742726
Other names: B. intestinihominis YIT 11860, Barnesiella intestinihominis YIT 11860, Barnesiella intestinihominis str. YIT 11860, Barnesiella intestinihominis strain YIT 11860
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.