| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EJZ61951.1 | EJZ61952.1 | HMPREF9448_02628 | HMPREF9448_02629 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | Hypothetical protein. | 0.775 |
| EJZ61951.1 | EJZ61953.1 | HMPREF9448_02628 | HMPREF9448_02630 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.854 |
| EJZ61951.1 | EJZ64549.1 | HMPREF9448_02628 | HMPREF9448_01027 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.685 |
| EJZ61951.1 | EJZ64814.1 | HMPREF9448_02628 | HMPREF9448_01300 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | 0.702 |
| EJZ61951.1 | EJZ64919.1 | HMPREF9448_02628 | HMPREF9448_01405 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | Por secretion system C-terminal sorting domain-containing protein. | 0.662 |
| EJZ61951.1 | EJZ65129.1 | HMPREF9448_02628 | HMPREF9448_00859 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | Hypothetical protein. | 0.672 |
| EJZ61951.1 | EJZ66457.1 | HMPREF9448_02628 | HMPREF9448_00635 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.695 |
| EJZ61951.1 | EJZ66528.1 | HMPREF9448_02628 | HMPREF9448_00707 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.686 |
| EJZ61951.1 | nadE | HMPREF9448_02628 | HMPREF9448_01297 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.730 |
| EJZ61951.1 | ribBA | HMPREF9448_02628 | HMPREF9448_02125 | Mutator mutT protein; Belongs to the Nudix hydrolase family. | Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.666 |
| EJZ61952.1 | EJZ61951.1 | HMPREF9448_02629 | HMPREF9448_02628 | Hypothetical protein. | Mutator mutT protein; Belongs to the Nudix hydrolase family. | 0.775 |
| EJZ61952.1 | EJZ61953.1 | HMPREF9448_02629 | HMPREF9448_02630 | Hypothetical protein. | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.791 |
| EJZ61953.1 | EJZ61951.1 | HMPREF9448_02630 | HMPREF9448_02628 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Mutator mutT protein; Belongs to the Nudix hydrolase family. | 0.854 |
| EJZ61953.1 | EJZ61952.1 | HMPREF9448_02630 | HMPREF9448_02629 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein. | 0.791 |
| EJZ61953.1 | ribBA | HMPREF9448_02630 | HMPREF9448_02125 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.722 |
| EJZ64549.1 | EJZ61951.1 | HMPREF9448_01027 | HMPREF9448_02628 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Mutator mutT protein; Belongs to the Nudix hydrolase family. | 0.685 |
| EJZ64549.1 | EJZ64814.1 | HMPREF9448_01027 | HMPREF9448_01300 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | 0.420 |
| EJZ64549.1 | EJZ66457.1 | HMPREF9448_01027 | HMPREF9448_00635 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.859 |
| EJZ64814.1 | EJZ61951.1 | HMPREF9448_01300 | HMPREF9448_02628 | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | Mutator mutT protein; Belongs to the Nudix hydrolase family. | 0.702 |
| EJZ64814.1 | EJZ64549.1 | HMPREF9448_01300 | HMPREF9448_01027 | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.420 |