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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGX68826.1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa)    
Predicted Functional Partners:
guaA
Hypothetical protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.958
EGX67088.1
Hypothetical protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 0.957
ade
Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
 
  
 0.954
EGX70985.1
Purine nucleoside phosphorylase.
     
 0.948
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.945
EGX67571.1
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.943
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.943
adk
Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 
 0.941
EGX67519.1
Inosine-5'-monophosphate dehydrogenase.
    
 0.938
ftsH-2
Hypothetical protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.934
Your Current Organism:
Collinsella tanakaei
NCBI taxonomy Id: 742742
Other names: C. tanakaei YIT 12063, Collinsella sp. YIT 12063, Collinsella tanakaei JCM 16071, Collinsella tanakaei YIT 12063, Collinsella tanakaei str. YIT 12063, Collinsella tanakaei strain YIT 12063
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