Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEM47796.1PFAM: Aminotransferase, class V/Cysteine desulfurase; KEGG: afr:AFE_1537 cysteine desulfurase. (394 aa)    
Predicted Functional Partners:
AEM47769.1
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
 
 0.986
AEM48572.1
PFAM: SirA-like; KEGG: afr:AFE_2557 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
   
 0.974
AEM47265.1
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.963
AEM47287.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: afr:AFE_0652 molybdopterin biosynthesis MoeB protein.
   
 0.945
AEM47790.1
KEGG: afr:AFE_1531 iron-sulfur cluster assembly accessory protein; TIGRFAM: FeS cluster insertion; PFAM: FeS cluster biogenesis; Belongs to the HesB/IscA family.
  
 
 0.877
AEM47772.1
NifQ family protein; PFAM: NifQ; KEGG: afr:AFE_1511 nitrogen fixation protein NifQ.
  
 0.858
AEM47800.1
PFAM: Ferredoxin; KEGG: afr:AFE_1541 ferredoxin, putative.
  
 0.832
AEM47803.1
KEGG: afr:AFE_3240 Rrf2 family protein; TIGRFAM: Transcriptional regulator, Rrf2; PFAM: Transcriptional regulator, Rrf2.
  
  
 0.808
AEM47793.1
PFAM: LRV FeS4 cluster; Leucine rich repeat variant; KEGG: afr:AFE_1534 leucine rich repeat protein.
 
     0.805
AEM47379.1
KEGG: afr:AFE_2195 CyaY protein; TIGRFAM: Frataxin-like; PFAM: Frataxin-like; Belongs to the frataxin family.
   
 0.796
Your Current Organism:
Acidithiobacillus ferrivorans
NCBI taxonomy Id: 743299
Other names: A. ferrivorans SS3, Acidithiobacillus ferrivorans SS3, Acidithiobacillus ferrivorans str. SS3, Acidithiobacillus ferrivorans strain SS3
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