Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEM49265.1PFAM: Methyltransferase type 12; KEGG: afr:AFE_3216 hypothetical protein. (179 aa)    
Predicted Functional Partners:
coq7
COQ7 family protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
   
 0.871
AEM48521.1
KEGG: afr:AFE_2388 2-octaprenyl-6-methoxyphenol hydroxylase; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6; PFAM: Monooxygenase, FAD-binding.
  
 0.808
AEM48522.1
KEGG: afr:AFE_2389 2-octaprenyl-6-methoxyphenol hydroxylase; TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6; PFAM: FAD dependent oxidoreductase.
  
 0.808
AEM49264.1
KEGG: afr:AFE_3215 lipoprotein, putative.
   
   0.791
mnmG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
    0.790
rsmG
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
     
 0.784
AEM49266.1
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
       0.783
AEM46942.1
KEGG: afe:Lferr_1541 hypothetical protein.
   
   0.747
AEM47701.1
KEGG: afe:Lferr_1541 hypothetical protein.
   
   0.747
AEM48803.1
2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
   
 
 0.735
Your Current Organism:
Acidithiobacillus ferrivorans
NCBI taxonomy Id: 743299
Other names: A. ferrivorans SS3, Acidithiobacillus ferrivorans SS3, Acidithiobacillus ferrivorans str. SS3, Acidithiobacillus ferrivorans strain SS3
Server load: low (14%) [HD]